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Folaţii sunt compuşi ai acidului pteroilglutamic, care funcţionează ca şi coenzime în reacţii metabolice care implică transferul unei unităţi de carbon. Folaţii şi vitamina B12 sunt esenţiali。

Ortiz Z, et al. Folic acid and folinic acid for reducing side effects in patients receiving methotrexate for rheumatoid arthritis (review). The Cochrane Collaboration. Published by JohnWileacid folic bioclinicay & Sons, Ltd. 2009.

The history of folic acid. British journal of haematology, 113(3), 579–589. British journal of haematology, 113(3), 579–589. Ionescu-Ittu, R. et al. (2009).

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